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On Tuesday, shares of Grail, the liquid biopsy company that hopes that its test, Galleri, will be widely used to screen for cancer, will become a publicly traded stock (with the ticker GRAL) that any investor can buy or sell on the Nasdaq.

That will, in a sense, end a long, strange trip that has taken a decade. Grail was spun out by the DNA sequencing giant Illumina in 2015. In 2020, Illumina announced plans to purchase the company for $8 billion. But that deal, though eventually closed, was scuttled by regulatory issues in both the U.S. and Europe, and European regulators forced Illumina to spin Grail back out.

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Grail now says it expects to file for full approval in the U.S. in 2026. In the meantime, the company is running an annual loss of about $500 million a year. As part of the agreement to spin it out, Illumina has capitalized it with about 2 1/2 years worth of funding.

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